Advances in Microbial Physiology, Vol. 49 by Robert K. Poole

By Robert K. Poole

First released in 1967, Advances in Microbial body structure is one among Elsevier's most famous and acclaimed sequence. Now edited by way of Professor Robert Poole, collage of Sheffield, Advances in Microbial body structure keeps to post topical and demanding stories, examining body structure in its broadest context, to incorporate all fabric that contributes to our figuring out of the way microorganisms and their part elements paintings. themes contain: * Glutathione, Altruistic Metabolite in Fungi * The position of the Flavodiiron Proteins in Microbial Nitric Oxide detoxing * tension Responsive micro organism: Biosensors as Environmental screens * Bacterial Na+ -or H+ - coupled ATP working at low electrochemical strength * Dissimiatory Fe(III) and Mn(IV) relief

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K. (1997) apd1 þ , a gene required for red pigment formation in ade6 mutants of Schizosaccharomyces pombe, encodes an enzyme required for glutathione biosynthesis: a role for glutathione and a glutathioneconjugate pump. Genetics 145, 75–83. G. J. (1995) Direct evidence for secondary loss of mitochondria in Entamoeba histolytica. Proc. Natl. Acad. Sci. USA 92, 6518–6521. S. S. (2003) Induction of apoptosis by sphingoid long-chain bases in Aspergillus nidulans. Mol. Cell. Biol. 23, 163–177. A. -J.

Biochim. Biophys. Acta 399, 10–22. M. V. (2001) Saccharomyces cerevisiae expresses three phopholipid hydroperoxide glutathione peroxidases. J. Biol. Chem. 276, 33730–33735. V. (2001) Metal toxicity in yeasts and the role of oxidative stress. Adv. Appl. Microbiol. 49, 111–142. -S. -O. (1999) gi|22653741|sp|Q9HF78|GSH1_CANAL[22653741] ô, direct submission to database. ô NCBI Entrez sequence identification number and data base accession number. M. and Veenhuis, M. (2002) Molecular characterization of the Hansenula polymorpha FLD1 gene encoding formaldehyde dehydrogenase.

To fulfil this fundamental function, the fungal cell does not need necessarily to use its full potential for the sythesis of GSH; often only minute amounts of the thiol are sufficient. There are several highly important enzyme systems associated with GSH. However, the chemical reactivity of the tripeptide, which modulates its implication in the cellular redox cycle, should not be forgotten! Undoubtedly, this is one of the most important features that explains the versatility of this compound. Once again, we must emphasize the deep influence exerted by investigators of mammalian physiology, like the late Alton Meister, on the development of GSH research.

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